abstract：BACKGROUND:Variations in the apolipoprotein E (apo E) gene may predict the incidence of coronary artery disease (CAD). However, the correlation between apo E polymorphism and the severity of CAD is still unclear. HYPOTHESIS:Apolipoprotein E polymorphism can predict CAD. METHODS:Used a case-case study of 213 Chinese a...

journal_title：Clinical cardiology

authors： Li SS,Yang J,Li LS,Wang HC

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Considering that prehypertension is associated with an increase in cardiovascular risk, hypoadiponectinemia seems to be a predictor of hypertension. HYPOTHESIS:This study investigated whether adiponectin plasma levels are affected in Brazilian obese prehypertensives compared with those in normotensives and ...

journal_title：Clinical cardiology

authors： Celoria BM,Genelhu VA,Pimentel Duarte SF,Delfraro PA,Francischetti EA

更新日期：2010-06-01 00:00:00

abstract：:Pregnant patients with mechanical prosthetic heart valves pose a great problem for medical management. The problem is even greater in a pregnant woman with mechanical valve thrombosis. This article describes a pregnant woman with prosthetic mitral valve thrombosis who had a successful fibrinolytic treatment. ...

journal_title：Clinical cardiology

authors： Kaya EB,Kocabaş U,Aksoy H,Aytemir K,Tokgözoğlu L

更新日期：2010-06-01 00:00:00

abstract：:Sertraline is a selective serotonin reuptake inhibitor with established safety for the treatment of depression. Among the common adverse effects associated with sertraline are nausea, insomnia, diarrhea, somnolence, and dizziness. Cardiac arrest had not been reported in the literature, although tachycardia was frequen...

journal_title：Clinical cardiology

authors： Kocabay G,Yildiz M,Eksi Duran N,Ozkan M

更新日期：2010-06-01 00:00:00

abstract：:At a recent Transcatheter Therapeutics meeting in San Francisco the PROSPECT Trial was presented by Dr. Greg Stone. Prospect stands for Providing Regional Observations to Study Predictors of Events in the Coronary Tree. This was a natural history study of atherosclerosis using multi-modality intracoronary imaging to p...

journal_title：Clinical cardiology

authors： Conti CR

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Takotsubo cardiomyopathy (TCM) is characterized by systolic ballooning of the left ventricular apex. It is triggered by emotional or physical stress, but the exact mechanism through which stress leads to TCM is not known. HYPOTHESIS:Coronary microvessel apoptosis is the missing link between stress and TCM. ...

journal_title：Clinical cardiology

authors： Uchida Y,Egami H,Uchida Y,Sakurai T,Kanai M,Shirai S,Nakagawa O,Oshima T

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Plaque rupture with subsequent transient thrombotic coronary occlusion by a fast-dissolving clot is one of the proposed pathogenic mechanisms in Takotsubo cardiomyopathy (TC). HYPOTHESIS:The aim of this study was to seek evidence for the hypothesis of transient coronary thrombosis as the underlying mechanis...

journal_title：Clinical cardiology

authors： Haghi D,Roehm S,Hamm K,Harder N,Suselbeck T,Borggrefe M,Papavassiliu T

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Inflammation is a key factor in the development of atherosclerotic disease and acute coronary syndromes (ACS). The P2Y(12) receptor antagonists ticagrelor (AZD6140) and clopidogrel may have anti-inflammatory effects. The objective of this analysis from the Dose Confirmation Study Assessing Anti-Platelet Effe...

journal_title：Clinical cardiology

authors： Husted S,Storey RF,Harrington RA,Emanuelsson H,Cannon CP

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Contrast-induced nephropathy (CIN) is the third cause of acute deterioration of renal function in hospitalized patients. HYPOTHESIS:The purpose of the study was to compare the efficacy of saline infusion, saline infusion plus N-acetylcysteine (NAC), and sodium bicarbonate (SB) infusion to prevent CIN in pat...

journal_title：Clinical cardiology

authors： Castini D,Lucreziotti S,Bosotti L,Salerno Uriarte D,Sponzilli C,Verzoni A,Lombardi F

更新日期：2010-03-01 00:00:00

abstract：:Type II heparin-induced thrombocytopenia (HIT) is a potentially severe adverse effect of heparin treatment triggered by an immune response. Although most cases occur in patients receiving unfractioned heparin, HIT can also arise after low-molecular-weight heparin (LMWH). We report a case of HIT in a postoperative orth...

journal_title：Clinical cardiology

authors： Mumoli N,Cei M

更新日期：2010-02-01 00:00:00

abstract：:ACC/AHA guidelines assign a class I indication for use of myocardial perfusion imaging (MPI) for the evaluation of chest pain in patients with acute coronary syndromes and a nondiagnostic ECG. However, MPI is not a widely used modality for the evaluation of patients who present to the ER with chest pain and an interme...

journal_title：Clinical cardiology

authors： Grube H,Rosenblatt J

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) risk is not fully revealed by traditional risk factors. Identification of a simple, noninvasive tool that allows for detection of high-risk CAD patients and can be applied in large populations and clinical settings would prove valuable. HYPOTHESIS:We sought to test the hypothes...

journal_title：Clinical cardiology

authors： Heffernan KS,Karas RH,Patvardhan EA,Jafri H,Kuvin JT

更新日期：2010-02-01 00:00:00

abstract：:In 2009, much was written about computed tomography (CT) angiography of the coronary circulation and little about catheter-based coronary angiography, despite its continued use since 1958 in patients with all types of cardiac disease or potential disease. ...

journal_title：Clinical cardiology

authors： Richard Conti C

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Management of acute coronary syndrome (ACS) patients with nonobstructive epicardial coronary artery disease (CAD) remains poorly understood. HYPOTHESIS:Acute coronary syndrome patients with nonobstructive CAD are less likely to receive effective cardiac medications upon discharge from the hospital. METHODS...

journal_title：Clinical cardiology

authors： Ramanath VS,Armstrong DF,Grzybowski M,Rahnama-Mohagdam S,Tamhane UU,Gordon K,Froehlich JB,Eagle KA,Jackson EA

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Ventricular arrhythmias are the most common consequences of structural and functional heart diseases, but cases with no evident pathology are also observed. A parameter indicating asymptomatic circulatory failure could support decisions related to possible treatment of ventricular arrhythmias. HYPOTHESIS:Th...

journal_title：Clinical cardiology

authors： Mazurek B,Szydłowski L,Giec-Fuglewicz G,Markiewicz-Łoskot G

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Limited information is available regarding outcome of very elderly patients referred for percutaneous coronary intervention (PCI). PURPOSE:This study aimed to assess acute and intermediate term clinical outcomes among nonagenarians. METHODS:The study included 32 consecutive nonagenarian patients undergoing...

journal_title：Clinical cardiology

authors： Parikh R,Chennareddy S,Debari V,Hamdan A,Konlian D,Shamoon F,Bikkina M

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Current guidelines for the use of implantable cardioverter-defibrillators (ICDs) are broad and significantly increase the cost of caring for patients with heart failure. In an effort to identify the specific subset of patients who benefit from this therapy, the predictive value of numerous echocardiographic ...

journal_title：Clinical cardiology

authors： Dorosz JL,Aaronson KD,Good ED,Kolias TJ

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Limited information exists regarding the association between subjective well-being (SWB) and systolic blood pressure (SBP) among hypertensive patients with coronary artery disease (CAD). HYPOTHESIS:We tested the hypothesis that there is an association between SBP and SWB. METHODS:We studied 22,576 hyperten...

journal_title：Clinical cardiology

authors： Gong Y,Handberg EM,Gerhard T,Cooper-Dehoff RM,Ried LD,Johnson JA,Pepine CJ,INVEST Investigators.

更新日期：2009-11-01 00:00:00

abstract：:Recommendations in the 2007 update of the American College of Cardiology/American Heart Association guidelines for patients with non-ST-elevation myocardial infarction (NSTEMI) provide considerable latitude regarding treatment choices and care pathways. Nevertheless, as accumulating evidence leads to increased recomme...

journal_title：Clinical cardiology

authors： Boden WE,Gupta V

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:C-reactive protein (CRP) and myeloperoxidase (MPO) are involved in the pathogenesis of atherosclerosis, mainly during periods of instabilization. This study aims to test the hypothesis that patients with acute coronary syndrome (ACS) maintain a persistent inflammatory state, and that this is associated with ...

journal_title：Clinical cardiology

authors： Borges FK,Borges FK,Stella SF,Souza JF,Wendland AE,Werres Junior LC,Ribeiro JP,Polanczyk CA

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Increased salt intake may induce hypertension, lead to cardiac hypertrophy, and exacerbate heart failure. When elderly patients develop heart failure, diastolic dysfunction is often observed, although the ejection fraction has decreased. Diabetes mellitus (DM) is an established risk factor for heart failure....

journal_title：Clinical cardiology

authors： Kagiyama S,Koga T,Kaseda S,Ishihara S,Kawazoe N,Sadoshima S,Matsumura K,Takata Y,Tsuchihashi T,Iida M

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:ECG U-wave inversion can be classified as initial and terminal U inversion according to the phasic relationship to positive U-wave deflection. Initial U inversion is occasionally observed in hypertensive patients while terminal U inversion frequently appears during severe myocardial ischemia. HYPOTHESIS:The...

journal_title：Clinical cardiology

authors： Miwa K

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Hypercholesterolemia is a risk factor for coronary artery disease, yet is associated with lower risk of adverse outcomes in patients with acute coronary syndromes (ACS). HYPOTHESIS:We explored this paradox in 84,429 patients with non-ST-segment elevation ACS in the Can Rapid Risk Stratification of Unstable ...

journal_title：Clinical cardiology

authors： Wang TY,Newby LK,Chen AY,Mulgund J,Roe MT,Sonel AF,Bhatt DL,DeLong ER,Ohman EM,Gibler WB,Peterson ED

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Until now there were no clinical studies or systematic reviews to investigate the impact of timing on efficacy and safety of intracoronary bone marrow stem cell (BMSC) transfer in patients with acute myocardial infarction (AMI). HYPOTHESIS:Timing of BMSC administration might play an important role in the th...

journal_title：Clinical cardiology

authors： Zhang S,Sun A,Xu D,Yao K,Huang Z,Jin H,Wang K,Zou Y,Ge J

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Identifying vulnerable plaque is important for preventing an acute coronary event. The present study examined the relationship between the clinical presentation of coronary artery disease and the plaque characteristics of nonculprit segment assessed by virtual histology intravascular ultrasound (VH-IVUS). M...

journal_title：Clinical cardiology

authors： Nakamura T,Kubo N,Funayama H,Sugawara Y,Ako J,Momomura S

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Recent data suggests that low molecular weight heparins (LMWHs) may be superior to unfractionated heparin (UFH) as an adjunct to fibrinolytic therapy in patients with acute ST-segment elevation myocardial infarction (STEMI). HYPOTHESIS:We evaluated cardiac outcomes and the risk of major bleeding with LMWHs ...

journal_title：Clinical cardiology

authors： Singh S,Bahekar A,Molnar J,Khosla S,Arora R

更新日期：2009-07-01 00:00:00

abstract：:The pseudoaneurysm is a rare cardiac pathology, in which the left ventricular free wall ruptures and the pericardium surrounds the rupture in combination with thrombus and inflammation and thus prevents the development of a hemopericardium. Left ventricular pseudoaneurysm may remain silent unless it gives rise to card...

journal_title：Clinical cardiology

authors： Bildirici U,Agacdiken A,Ural E,Kahraman G,Komsuoglu B

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Numerous evidence has suggested that either hypertension or atrial fibrillation (AF) is associated with systemic inflammation. Peroxisome proliferator-activated receptor-gamma (PPARgamma) has been proved to have anti-inflammatory effects and is implicated as a molecular pathway involved in many cardiovascula...

journal_title：Clinical cardiology

authors： Chen X,Bing Z,He J,Jiang L,Luo X,Su Y,Kan B,Huang D,Wei Y

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:For patients with ST elevation myocardial infarction (STEMI) or non-ST elevation myocardial infarction (NSTEMI), rapid restoration of coronary blood flow is the primary therapeutic goal. Because of the acute nature of this clinical presentation, bleeding risks may not be adequately evaluated, limiting the us...

journal_title：Clinical cardiology

authors： Wöhrle J,Nusser T,Langenwalder S,Heombach V,Kochs M

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Rarely occurring in the pediatric and adolescent population, aortic dissection is a condition with many predisposing factors. Previous studies have suggested that congenital cardiovascular disorders are the most common predisposing conditions. Trauma-associated aortic dissection is considered a rare occurren...

journal_title：Clinical cardiology

authors： Fikar CR,Fikar R

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Slow coronary flow in patients without obstructive coronary artery disease is an angiographic finding that could easily be detected by thrombolysis in myocardial infarction (TIMI) frame counts. On the other hand, impaired renal function is a frequent problem. We searched the association between the 2 entitie...

journal_title：Clinical cardiology

authors： Yilmaz MB,Yalta K

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Percutaneous interventions for aorto-ostial narrowing of native coronary arteries are challenging because of early elastic recoil after the procedure and the high restenosis rate. Cutting balloon angioplasty may reduce this complication. HYPOTHESIS:The purpose of the study was to evaluate the clinical outco...

journal_title：Clinical cardiology

authors： Nassar H,Gotsman I,Gerganski P,Moseri M,Lotan C,Gotsman M

更新日期：2009-04-01 00:00:00

abstract：:In this editorial, I would like to share some thoughts about clinical studies, including value and limitations using as an example a recently published randomized clinical trial. Randomized and non-randomized clinical trials, epidemiologic studies, and registries guide our clinical practice. They are good but not perf...

journal_title：Clinical cardiology

authors： Richard Conti C

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The poor clinical outcome in acute myocardial infarction (AMI) patients undergoing primary percutaneous coronary intervention (PCI) has been attributed to myocardial ischemia-reperfusion injury (MIRI). OBJECTIVE:This study aimed to identify the predictive factors of MIRI during PCI in Chinese AMI patients w...

journal_title：Clinical cardiology

authors： Luo Y,Li GL,Pan YZ,Zhou SF

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Anticoagulation with heparin is recommended with intra-aortic balloon pump (IABP) to prevent thrombosis and embolization. However, anticoagulation increases the risk of bleeding, particularly in combination with glycoprotein (GP) IIb/IIIa antagonists. HYPOTHESIS:We investigated the safety of using GP IIb/II...

journal_title：Clinical cardiology

authors： Laish-Farkash A,Hod H,Matetzky S,Guetta V

更新日期：2009-02-01 00:00:00

abstract：:Cardiac troponins (CTn) are the most sensitive and specific biochemical markers of myocardial injury and risk stratification. The assay for troponin T (cTnI) is standardized, and results obtained from different institutions are comparable. This is not the case with troponin I (cTnT), and clinicians should be aware tha...

journal_title：Clinical cardiology

authors： Agzew Y

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Insulin resistance is clearly associated with coronary artery disease (CAD) in diabetics. Insulin resistance may also be present in normoglycemic individuals, and some of these patients can be diagnosed as having metabolic syndrome (MS) according to various definitions. However, the relationship between hype...

journal_title：Clinical cardiology

authors： Deveci E,Yesil M,Akinci B,Yesil S,Postaci N,Arikan E,Koseoglu M

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The efficacy of prophylactic coronary revascularization with percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery in patients with abdominal aortic aneurysm (AAA) scheduled for open repair surgery remains controversial. HYPOTHESIS:Concomitant coronary artery disease (CAD) ...

journal_title：Clinical cardiology

authors： Hosokawa Y,Takano H,Aoki A,Inami T,Ogano M,Kobayashi N,Tanabe J,Yokoyama H,Kato T,Takagi H,Umemoto T,Takayama M,Mizuno K

更新日期：2008-12-01 00:00:00

abstract：BACKGROUNDS:The causes and prognosis of pericardial effusion (PE) may be different according to time, region, economy, and hospital. This study was performed to evaluate the etiology, clinical outcome, and prognosis of patients with large, symptomatic PE treated by echo-guided pericardiocentesis at Kangnam St. Mary's H...

journal_title：Clinical cardiology

authors： Kil UH,Jung HO,Koh YS,Park HJ,Park CS,Kim PJ,Baek SH,Seung KB,Choi KB

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Early recurrence of atrial fibrillation (ERAF) after catheter ablation is common and has been thoroughly studied. However, very late recurrence of atrial fibrillation (VLRAF) is rarely researched, and its characteristics have not been determined. HYPOTHESIS:The aim of this study was to investigate the clini...

journal_title：Clinical cardiology

authors： Tao H,Liu X,Dong J,Long D,Tang R,Zheng B,Kang J,Yu R,Tian Y,Ma C

更新日期：2008-10-01 00:00:00